Ethical & Independent Review Services (E&I)

is an AAHRPP accredited, service-oriented company that provides IRB review of human subjects research.

E&I is privately owned and operated, without any involvement of venture capital or private equity firms. We take pride in our modest size and our independent ownership, which maintains a clear, specific and primary objective to protect human subjects, above all else (including profit.)

It has been our experience, that participant protection begins with an open, responsive, and guidance-driven relationship between the IRB and the investigators, research teams and sponsors who lead the studies we review. We make this a priority.

When you work with E&I, you can trust us to be a partner in your program to protect research participants.


You can find our compliance statement here

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Please note that our business office has moved!

Our new address is 304 SE Third Street, Lee's Summit, MO 64063

COVID-19 Reporting

If you are making temporary process changes to your approved protocol due to COVID-19 risks or restrictions, reach out to the E&I administration for guidance on documentation.
We are ready to help.

sIRB Requirement

Effective January 25, 2018, the NIH mandated that all domestic sites participating in a non-exempt, multi-site research study (where study activities outlined in a single protocol are carried out at multiple institutions) use a single IRB (sIRB).

Effective January 20, 2020, OHRP will require a sIRB for all domestic sites participating in a non-exempt, cooperative research study (two or more institutions coordinate to complete a portion of the research outlined in a specific protocol).

If you need assistance meeting this obligation, let us know. We can help.